GPRC6A Protein (AA 456-590) (His tag)

Produktnummer ABIN7505527

Produktdetails

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 456-590

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GPRC6A Protein ist gelabelt mit His tag.

Sequenz: Thr 456-Asp 590

Produktmerkmale: A DNA sequence encoding the Rat GPRC6A protein (Q70VB1) (Thr 456-Asp 590) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Andere Bezeichnung: GPRC6A (GPRC6A Produkte)

Synonyme: gpcr Protein, GPCR Protein, bA86F4.3 Protein, G protein-coupled receptor class C group 6 member A Protein, G protein-coupled receptor, family C, group 6, member A Protein, G protein-coupled receptor, class C, group 6, member A Protein, GPRC6A Protein, gprc6a Protein, Gprc6a Protein

Hintergrund:

Abbreviation: GPRC6A

Target Synonym: bA86F4.3,G protein coupled receptor 33,G-protein coupled receptor family C group 6 member A,GPC6A,GPCR33,Predicted with SOSUI analysis,seven transmembrane helix receptor

Background: Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.

Molekulargewicht:

Calculated MW: 14.74 kDa

Observed MW: 25 kDa

UniProt: Q70VB1