IL1A Protein (AA 115-270) (His tag)

Produktnummer ABIN7505547

Produktdetails

Target: IL1A (Interleukin 1 alpha (IL1A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 115-270

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses IL1A Protein ist gelabelt mit His tag.

Sequenz: Ser 115-Ser 270

Produktmerkmale: A DNA sequence encoding the Rat IL1A/IL-1F1 protein (P16598) (Ser 115-Ser 270) was expressed with N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL1A (Interleukin 1 alpha (IL1A))

Andere Bezeichnung: IL1A (IL1A Produkte)

Synonyme: IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein

Hintergrund:

Abbreviation: IL1A,IL-1F1

Target Synonym: BAF,Hematopoietin-1,IL1 alpha,IL-1 alpha,IL1,IL1A,IL-1A,IL1-ALPHA,IL1F1,IL-1F1,IL1F1hematopoietin-1,interleukin 1,alpha,interleukin-1 alpha,LAF,LEM,preinterleukin 1 alpha,pro-interleukin-1-alpha

Background: IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signaling.

Molekulargewicht:

Calculated MW: 17.05 kDa

Observed MW: 16 kDa

UniProt: P16598

Pathways: NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints