IGFBPI Protein (AA 26-272) (His tag)

Produktnummer ABIN7505552

Produktdetails

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-272

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses IGFBPI Protein ist gelabelt mit His tag.

Sequenz: Ala 26-Asn 272

Produktmerkmale: A DNA sequence encoding the Rat IGFBP1/IGFBP-1 protein (P21743) (Ala 26-Asn 272) was expressed with N-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Andere Bezeichnung: IGFBP1 (IGFBPI Produkte)

Synonyme: cb656 Protein, igfbp1 Protein, IGFBP-1 Protein, MGC68538 Protein, afbp Protein, ibp1 Protein, pp12 Protein, igf-bp25 Protein, higfbp-1 Protein, IGFBP1 Protein, LOC100223208 Protein, LOC100305121 Protein, AFBP Protein, IBP1 Protein, IGF-BP25 Protein, PP12 Protein, hIGFBP-1 Protein, IGFBA Protein, insulin like growth factor binding protein 1 Protein, insulin-like growth factor binding protein 1a Protein, insulin like growth factor binding protein 1 S homeolog Protein, insulin like growth factor binding protein 1 L homeolog Protein, insulin-like growth factor binding protein 1 Protein, IGFBP1 Protein, igfbp1a Protein, igfbp1.S Protein, igfbp1.L Protein, igfbp1 Protein, LOC100305121 Protein, Igfbp1 Protein

Hintergrund:

Abbreviation: IGFBP1,IGFBP-1

Target Synonym: Insulin-like growth factor-binding protein 1,Igfbp1,IBP-1,IGF-binding protein 1,IGFBP-1

Background: The insulin-like growth factor binding protein (IGFBP) family consists of six structurally related proteins that bind IGF with high affinity. These proteins share conserved cysteine-rich N- and C- terminal regions that participate in IGF binding. IGFBPs regulate the bioavailability of IGFs and modulate their biological activities, both positively and negatively. Some IGFBPs also have intrinsic bioactivity that is IGF-independent. Post-transitional modifications of the IGFBPs, including glycosylation, phosphorylation and proteolysis, influence IGF binding affinities and tissue localization, affecting both the IGF-dependent and independent functions.

Molekulargewicht:

Calculated MW: 27.06 kDa

Observed MW: 35 kDa

UniProt: P21743

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding