IL-8 Protein (AA 21-99) (His tag)

Produktnummer ABIN7505578

Produktdetails

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-99

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL-8 Protein ist gelabelt mit His tag.

Sequenz: Glu21-Ser99

Produktmerkmale: Recombinant Human C-X-C motif chemokine 8/Interleukin 8 is produced by our Mammalian expression system and the target gene encoding Glu21-Ser99 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Andere Bezeichnung: IL-8 (IL8 Produkte)

Synonyme: CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein

Hintergrund:

Abbreviation: IL-8,CXCL8

Target Synonym: Interleukin-8,IL-8,C-X-C Motif Chemokine 8,CXCL8,Emoctakin,Granulocyte Chemotactic Protein 1,GCP-1,Monocyte-Derived Neutrophil Chemotactic Factor,MDNCF,Monocyte-Derived Neutrophil-Activating Peptide,MONAP,Neutrophil-Activating Protein 1,NAP-1

Background: Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.

Molekulargewicht:

Calculated MW: 10.1 kDa

Observed MW: 14 kDa

UniProt: P10145

Pathways: TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie