LILRB1 Protein (AA 24-458) (His tag)

Produktnummer ABIN7505583

Produktdetails

Target: LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 24-458

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LILRB1 Protein ist gelabelt mit His tag.

Sequenz: Gly24-His458

Produktmerkmale: Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))

Andere Bezeichnung: LILRB1 (LILRB1 Produkte)

Synonyme: CD85J Protein, ILT-2 Protein, ILT2 Protein, LIR-1 Protein, LIR1 Protein, MIR-7 Protein, MIR7 Protein, leukocyte immunoglobulin like receptor B1 Protein, LILRB1 Protein

Hintergrund:

Abbreviation: LILRB1

Target Synonym: Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1,LIR-1,Leukocyte Immunoglobulin-Like Receptor 1,CD85 Antigen-Like Family Member J,Immunoglobulin-Like Transcript 2,ILT-2,Monocyte/Macrophage Immunoglobulin-Like Receptor 7,MIR-7,CD85j,LILRB1,ILT2,LIR1,MIR7

Background: The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.

Molekulargewicht:

Calculated MW: 48.2 kDa

Observed MW: 79 kDa

UniProt: D9IDM8

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response