IL1A Protein (AA 1-271)

Produktnummer ABIN7505592

Produktdetails

Target: IL1A (Interleukin 1 alpha (IL1A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-271

Spezies: Human

Quelle: HEK-293 Cells

Sequenz: Met1-Ala271

Produktmerkmale: A DNA sequence encoding the Human IL-1α protein (P01583) (1-271) was expressed with a polyhistidine tag at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL1A (Interleukin 1 alpha (IL1A))

Andere Bezeichnung: IL-1alpha (IL1A Produkte)

Hintergrund:

Abbreviation: IL-1α

Target Synonym: IL-1 alpha,Hematopoietin-1,IL1A,IL1F1,Interleukin-1 alpha,IL1a

Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Molekulargewicht:

Calculated MW: 30.6 kDa

Observed MW: 35 kDa

UniProt: P01583

Pathways: NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints