IL12 Protein (AA 23-328)

Produktnummer ABIN7505595

Produktdetails

Target: IL12 (Interleukin 12 (IL12))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-328

Spezies: Human

Quelle: HEK-293 Cells

Sequenz: Ile23-Ser328

Produktmerkmale: A DNA sequence encoding the Human IL12(P40) Protein(P29460)(23-328)was expressed with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL12 (Interleukin 12 (IL12))

Andere Bezeichnung: IL12 (IL12 Produkte)

Hintergrund:

Abbreviation: IL-12

Target Synonym: Interleukin-12 subunit beta,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,Il12b,NKSF2

Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Molekulargewicht:

Calculated MW: 35 kDa

Observed MW: 38 kDa

UniProt: P29460

Pathways: JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome