LPA Protein (AA 1719-2038) (His tag)
-
- Target Alle LPA (APOA) Proteine anzeigen
- LPA (APOA) (Apolipoprotein A (APOA))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1719-2038
- Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses LPA Protein ist gelabelt mit His tag.
- Sequenz
- Asp1719-Arg2038
- Produktmerkmale
- A DNA sequence encoding the Human LP-a protein (P08519) (Asp1719-Arg2038) was expressed with a C-His.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product APOA Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
-
- Target
- LPA (APOA) (Apolipoprotein A (APOA))
- Andere Bezeichnung
- Lipoprotein A (APOA Produkte)
- Synonyme
- AK38 Protein, APOA Protein, LP Protein, Apo(a) Protein, Lp(a) Protein, lipoprotein(a) Protein, LPA Protein
- Hintergrund
-
Abbreviation: Apolipoprotein,Lp
Target Synonym: APOA,Apolipoprotein(a),Apo(a),Lp(a),LPA,Lp(a)
Background: Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.
- Molekulargewicht
-
Calculated MW: 35.09 kDa
Observed MW: 35 kDa
- UniProt
- P08519
-
