MMP3 Protein (AA 1-477) (His tag)

Produktnummer ABIN7505634

Produktdetails

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-477

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MMP3 Protein ist gelabelt mit His tag.

Sequenz: Met1-Cys477

Produktmerkmale: A DNA sequence encoding the Human MMP3 protein (P08254) (Met1-Cys477) was expressed with a C-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Andere Bezeichnung: MMP3 (MMP3 Produkte)

Synonyme: CHDS6 Protein, MMP-3 Protein, SL-1 Protein, STMY Protein, STMY1 Protein, STR1 Protein, SLN-1 Protein, SLN1 Protein, STR-1 Protein, Stmy1 Protein, Str1 Protein, MMP10 Protein, chds6 Protein, mmp-3 Protein, mmp13 Protein, mmp3 Protein, sl-1 Protein, stmy Protein, stmy1 Protein, str1 Protein, matrix metallopeptidase 3 Protein, matrix metallopeptidase 3 (stromelysin 1, progelatinase) Protein, matrix metallopeptidase 3 L homeolog Protein, MMP3 Protein, Mmp3 Protein, mmp3.L Protein

Hintergrund:

Abbreviation: MMP3

Target Synonym: Stromelysin-1,SL-1,Matrix metalloproteinase-3,Transin-1,MMP3,STMY1,CHDS6,MMP-3,SL-1,STMY,STR1

Background: MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

Molekulargewicht:

Calculated MW: 52.36 kDa

Observed MW: 59 kDa

UniProt: P08254