APOE Protein (AA 1-317) (His tag)

Produktnummer ABIN7505686

Produktdetails

Target: APOE (Apolipoprotein E (APOE))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-317

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses APOE Protein ist gelabelt mit His tag.

Sequenz: Met1-His317

Produktmerkmale: A DNA sequence encoding the Human ApoE protein (P02649) (Met1-His317) was expressed with a C-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: Apolipoprotein E (APOE Produkte)

Synonyme: ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein

Hintergrund:

Abbreviation: Apolipoprotein E,ApoE

Target Synonym: Apolipoprotein E,APOE,Apo-E

Background: ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apolipoprotein E combines with fats (lipids) in the body to form molecules called lipoproteins and Apolipoprotein E is a major component of a specific type of lipoprotein called very low-density lipoproteins (VLDLs).

Molekulargewicht:

Calculated MW: 34.76 kDa

Observed MW: 38 kDa

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism