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CD200 Protein (CD200) (AA 1-232) (His tag)

CD200 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505709
  • Target Alle CD200 Proteine anzeigen
    CD200
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-232
    Spezies
    • 18
    • 7
    • 2
    • 1
    Human
    Quelle
    • 13
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD200 Protein ist gelabelt mit His tag.
    Sequenz
    Met1-Gly232
    Produktmerkmale
    A DNA sequence encoding the Human CD200 protein (P41217) (Met1-Gly232) was expressed with a C-His.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CD200 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    CD200
    Andere Bezeichnung
    CD200 (CD200 Produkte)
    Synonyme
    MOX1 Protein, MOX2 Protein, MRC Protein, OX-2 Protein, CD200 Protein, Cspmo2 Protein, MRCOX2 Protein, Mox2 Protein, DKFZp459C0716 Protein, OX2 Protein, CD200 molecule Protein, Cd200 molecule Protein, CD200 antigen Protein, CD200 Protein, Cd200 Protein
    Hintergrund

    Abbreviation: CD200

    Target Synonym: OX-2 Membrane Glycoprotein,CD200,MOX1,MOX2

    Background: CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals following receptor-ligand contact. In T cells, CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

    Molekulargewicht

    Calculated MW: 25.41 kDa

    Observed MW: 35 kDa

    UniProt
    P41217
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