PNLIP Protein (AA 1-465) (His tag)

Produktnummer ABIN7505814

Produktdetails

Target: PNLIP (Pancreatic Lipase (PNLIP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-465

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PNLIP Protein ist gelabelt mit His tag.

Sequenz: Met 1-Cys465

Produktmerkmale: A DNA sequence encoding the Human PL protein (P16233) (1-465) was expressed with a C-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PNLIP (Pancreatic Lipase (PNLIP))

Abstract: PNLIP Produkte

Synonyme: PL Protein, PNLIPD Protein, PTL Protein, LIPASE Protein, PANLI Protein, 1810007A24Rik Protein, PNLIP Protein, PNLIPRP2 Protein, pancreatic lipase Protein, PNLIP Protein, Pnlip Protein, pnlip Protein

Hintergrund:

Abbreviation: PL,PNLIP

Target Synonym: Pancreatic triacylglycerol lipase,PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3)

Background: PNLIP is an enzyme which belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the lipase to break apart the fat more effectively. The resulting monomers (2 free fatty acids and one 2-monoacylglycerol) are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal.

Molekulargewicht:

Calculated MW: 51.04 kDa

Observed MW: 50 kDa

UniProt: P16233