APOH Protein (His tag)
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- Target Alle APOH Proteine anzeigen
- APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses APOH Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Apolipoprotein H/ApoH Protein
- Sequenz
- GRTCPKPDDL PFSTVVPLKT FYEPGEEITY SCKPGYVSRG GMRKFICPLT GLWPINTLKC TPRVCPFAGI LENGAVRYTT FEYPNTISFS CNTGFYLNGA DSAKCTEEGK WSPELPVCAP IICPPPSIPT FATLRVYKPS AGNNSLYRDT AVFECLPQHA MFGNDTITCT THGNWTKLPE CREVKCPFPS RPDNGFVNYP AKPTLYYKDK ATFGCHDGYS LDGPEEIECT KLGNWSAMPS CKASCKVPVK KATVVYQGER VKIQEKFKNG MLHGDKVSFF CKNKEKKCSY TEDAQCIDGT IEVPKCFKEH SSLAFWKTDA SDVKPC
- Spezifität
- Gly20-Cys345
- Reinheit
- > 95 % by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- <0.1EU/μg
- Top Product
- Discover our top product APOH Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
- Andere Bezeichnung
- Apolipoprotein H/ApoH (APOH Produkte)
- Synonyme
- B2G1 Protein, B2GP1 Protein, BG Protein, BETA2 Protein, BHF-1 Protein, MODY6 Protein, NEUROD Protein, bHLHa3 Protein, apoh Protein, APOH Protein, B2GPI Protein, beta-2-GPI Protein, beta2-GPI Protein, LOC100227913 Protein, apolipoprotein H Protein, neuronal differentiation 1 Protein, APOH Protein, NEUROD1 Protein, apoh Protein, Apoh Protein
- Hintergrund
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Description: Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. APOH appears to completely inhibit serotonin release by the platelets and prevents subsequent waves of the ADP-induced aggregation. The activity of APOH appears to involve the binding of agglutenating, negatively charged compounds, and inhibits agglutenation by the contact activation of the intrinsic blood coagulation pathway.
Name: APOH,B2G1,B2GP1,BG
- Gen-ID
- 350
- UniProt
- P02749
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