CCL6 Protein (His tag)
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- Target Alle CCL6 Proteine anzeigen
- CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CCL6 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse CCL6 Protein
- Sequenz
- GLIQEMEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
- Spezifität
- Gly22 - Ala116
- Reinheit
- > 97 % by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- <1EU/μg
- Top Product
- Discover our top product CCL6 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Konzentration
- 1.3 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))
- Andere Bezeichnung
- CCL6 (CCL6 Produkte)
- Synonyme
- MRP-1 Protein, Scya6 Protein, c10 Protein, Abcc1a Protein, Avcc1a Protein, Mrp Protein, Mrp1 Protein, Mrp-1 Protein, Scay6 Protein, chemokine (C-C motif) ligand 6 Protein, ATP binding cassette subfamily C member 1 Protein, Ccl6 Protein, Abcc1 Protein
- Hintergrund
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Description: Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears to contribute to the macrophage infiltration that is independent of other CC chemokines. C10 is a prominent chemokine expressed in the central nervous system in experimental inflammatory demyelinating disease, also acts as a potent chemotactic factor for the migration of these leukocytes to the brain. CCL6 may be a mediator released by microglia for cell-cell communication under physiological as well as pathological conditions of CNS. Additionally, the chemokine CCL6 may alter tumor behavior by relieving its growth factor dependency and by promoting invasiveness as a result of local tissue apoptosis.
Name: c10, MRP-1, Scya6,CCL6
- Gen-ID
- 20305
- UniProt
- P27784
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