CSH1 Protein (His tag)
-
- Target Alle CSH1 Proteine anzeigen
- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CSH1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Chorionic somatomammotropin hormone 1/Choriomammotropin/CSH1 Protein
- Sequenz
- VQTVPLSRLF DHAMLQAHRA HQLAIDTYQE FEETYIPKDQ KYSFLHDSQT SFCFSDSIPT PSNMEETQQK SNLELLRISL LLIESWLEPV RFLRSMFANN LVYDTSDSDD YHLLKDLEEG IQTLMGRLED GSRRTGQILK QTYSKFDTNS HNHDALLKNY GLLYCFRKDM DKVETFLRMV QCRSVEGSCG F
- Spezifität
- Val27-Phe217
- Reinheit
- > 97 % by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- <0.001EU/μg
- Top Product
- Discover our top product CSH1 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Konzentration
- 0.7 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
- Target
- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
- Andere Bezeichnung
- Chorionic somatomammotropin hormone 1/Choriomammotropin/CSH1 (CSH1 Produkte)
- Synonyme
- CS-1 Protein, CSA Protein, CSMT Protein, PL Protein, hCS-A Protein, CS-2 Protein, CSB Protein, hCS-B Protein, chorionic somatomammotropin hormone 1 Protein, chorionic somatomammotropin hormone 2 Protein, CSH1 Protein, CSH2 Protein
- Hintergrund
-
Description: Chorionic somatomammotropin hormone, also known as Choriomammotropin, Lactogen, Placental lactogen and CSH1, is a secreted protein which belongs to thesomatotropin / prolactin family. CSH1 is produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. The CSH1 gene is member of the GH gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. Genomic alterations in the GH cluster are well known, causing different phenotypes depending on the size of the deletion and the genes involved. The increased prevalence of hemizygosity of CSH1 in population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation. Investigation of CSH1 deletions in further SRS and growth retarded patients will enable us to establish under which circumstances haploinsufficiency of CSH1 is likely to result in clinical changes.
Name: PL, CSA, CS-1, CSMT, GHB3, hCS-1, hCS-A
- Gen-ID
- 1442
- UniProt
- P0DML2
- Pathways
- Response to Growth Hormone Stimulus
-