EPOR Protein (His tag)

Produktnummer ABIN7536274

Produktdetails

Target: EPOR (Erythropoietin Receptor (EPOR))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EPOR Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse EPO-R/Epor Protein

Sequenz: APSPSLPDPK FESKAALLAS RGSEELLCFT QRLEDLVCFW EEAASSGMDF NYSFSYQLEG ESRKSCSLHQ APTVRGSVRF WCSLPTADTS SFVPLELQVT EASGSPRYHR IIHINEVVLL DAPAGLLARR AEEGSHVVLR WLPPPGAPMT THIRYEVDVS AGNRAGGTQR VEVLEGRTEC VLSNLRGGTR YTFAVRARMA EPSFSGFWSA WSEPASLLTA SDLDP

Spezifität: Ala25-Pro249

Reinheit: > 97 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Konzentration: 0.36 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: EPOR (Erythropoietin Receptor (EPOR))

Andere Bezeichnung: EPO-R/Epor (EPOR Produkte)

Synonyme: EPOR Protein, epor Protein, EPO-R Protein, erythropoietin receptor Protein, erythropoietin receptor L homeolog Protein, EPOR Protein, epor Protein, Epor Protein, epor.L Protein

Hintergrund:

Description: Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a... single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.

Name: EPO-R,Epor

Gen-ID: 13857

UniProt: P14753

Pathways: JAK-STAT Signalweg