IL1RL2 Protein (His tag)

Produktnummer ABIN7520130

Produktdetails

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL1RL2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human IL-36R/IL-1Rrp2/IL1RL2 Protein

Sequenz: DGCKDIFMKN EILSASQPFA FNCTFPPITS GEVSVTWYKN SSKIPVSKII QSRIHQDETW ILFLPMEWGD SGVYQCVIKG RDSCHRIHVN LTVFEKHWCD TSIGGLPNLS DEYKQILHLG KDDSLTCHLH FPKSCVLGPI KWYKDCNEIK GERFTVLETR LLVSNVSAED RGNYACQAIL THSGKQYEVL NGITVSITER AGYGGSVPKI IYPKNHSIEV QLGTTLIVDC NVTDTKDNTN LRCWRVNNTL VDDYYDESKR IREGVETHVS FREHNLYTVN ITFLEVKMED YGLPFMCHAG VSTAYIILQL PAPDFR

Spezifität: Asp20-Arg335

Reinheit: > 95 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Andere Bezeichnung: IL-36R/IL-1Rrp2/IL1RL2 (IL1RL2 Produkte)

Synonyme: IL-1Rrp2 Protein, IL-36R Protein, IL1R-rp2 Protein, IL1RRP2 Protein, AI481289 Protein, AW551444 Protein, interleukin 1 receptor like 2 Protein, interleukin 1 receptor-like 2 Protein, IL1RL2 Protein, Il1rl2 Protein

Hintergrund:

Description: IL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R) is a Protein Coding gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. This gene and four other interleukin 1 receptor family genes form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. The IL36 receptor is an important mediator molecule in the inflammatory response. Animal data suggest that IL1RL2 is involved in mucosal healing. Therapeutic intervention of IL-36R signaling offers an innovative treatment paradigm for targeting epithelial cell-mediated inflammatory diseases such as the life-threatening psoriasis variant called generalized pustular psoriasis (GPP). Diseases associated with IL1RL2 include Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue.

Name: IL1RL2,IL-1Rrp2,IL-36R,IL1R-rp2,IL1RRP2,IL36R

Gen-ID: 8808

UniProt: Q9HB29