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P-Cadherin Protein (CDH3) (His tag)

CDH3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 85 % by SDS-PAGE. Active
Produktnummer ABIN7520380
  • Target Alle P-Cadherin (CDH3) Proteine anzeigen
    P-Cadherin (CDH3)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 6
    • 1
    • 1
    Human
    Quelle
    • 5
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses P-Cadherin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Active Recombinant Human CDH3/P-cadherin Protein
    Sequenz
    DWVVAPISVP ENGKGPFPQR LNQLKSNKDR DTKIFYSITG PGADSPPEGV FAVEKETGWL LLNKPLDREE IAKYELFGHA VSENGASVED PMNISIIVTD QNDHKPKFTQ DTFRGSVLEG VLPGTSVMQV TATDEDDAIY TYNGVVAYSI HSQEPKDPHD LMFTIHRSTG TISVISSGLD REKVPEYTLT IQATDMDGDG STTTAVAVVE ILDANDNAPM FDPQKYEAHV PENAVGHEVQ RLTVTDLDAP NSPAWRATYL IMGGDDGDHF TITTHPESNQ GILTTRKGLD FEAKNQHTLY VEVTNEAPFV LKLPTSTATI VVHVEDVNEA PVFVPPSKVV EVQEGIPTGE PVCVYTAEDP DKENQKISYR ILRDPAGWLA MDPDSGQVTA VGTLDREDEQ FVRNNIYEVM VLAMDNGSPP TTGTGTLLLT LIDVNDHGPV PEPRQITICN QSPVRQVLNI TDKDLSPHTS PFQAQLTDDS DIYWTAEVNE EGDTVVLSLK KFLKQDTYDV HLSLSDHGNK EQLTVIRATV CDCHGHVETC PGPWKGG
    Spezifität
    Asp108-Gly654
    Reinheit
    > 85 % by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    <1EU/μg
    Biological Activity Comment
    Measured by the ability of the immobilized protein to support the adhesion of A431 human epithelial carcinoma cells. When 1x105 cells/well are added to rhP-CAD/Fc Chimera coated plates (10 μg/mL with 100 μL/well), approximately 50-60% will adhere after 1.5 hours at 37° C.
    Top Product
    Discover our top product CDH3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    P-Cadherin (CDH3)
    Andere Bezeichnung
    CDH3/P-cadherin (CDH3 Produkte)
    Synonyme
    CDH3 Protein, Cadherin-3 Protein, AI385538 Protein, Cadp Protein, Cdhp Protein, P-cadherin Protein, Pcad Protein, CDHP Protein, HJMD Protein, PCAD Protein, E-Cad Protein, E-cadherin Protein, EP-cadherin Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, cdh1 Protein, cdh1-b Protein, cdh3 Protein, cdhc-A Protein, cdhp Protein, hjmd Protein, l-cam Protein, lcam Protein, pcad Protein, uvo Protein, uvomorulin Protein, xb-cad Protein, xcdh1 Protein, CDH15 Protein, K-CAM Protein, cadherin 3 Protein, cadherin 3 L homeolog Protein, Cadherin-3 Protein, CDH3 Protein, Cdh3 Protein, cdh3.L Protein, cdh-3 Protein
    Hintergrund

    Description: Cadherin-3 (also known as P-cadherin)is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.

    Name: CDH3,CDHP,HJMD,PCAD

    Gen-ID
    1001
    UniProt
    P22223
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