S100A12 Protein (His tag)

Produktnummer ABIN7533717

Produktdetails

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses S100A12 Protein ist gelabelt mit His tag.

Verwendungszweck: Active Recombinant Human S100-A12 Protein

Sequenz: MTKLEEHLEG IVNIFHQYSV RKGHFDTLSK GELKQLLTKE LANTIKNIKD KAVIDEIFQG LDANQDEQVD FQEFISLVAI ALKAAHYHTH KE

Spezifität: Met1-Glu92

Reinheit: > 97 % by SDS-PAGE.

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human S100A12 at 2 μg/mL (100 μL/well) can bind recombinant Human AGER/RAGE with a linear range of 0.1-27.25 ng/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.877 mg/mL

Buffer: Supplied in PBS, 25 % glycerol, pH 7.4

Lagerung: -80 °C

Informationen zur Lagerung: This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.

Antigendetails

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Andere Bezeichnung: S100-A12 (S100A12 Produkte)

Synonyme: CAAF1 Protein, CAGC Protein, CGRP Protein, ENRAGE Protein, MRP-6 Protein, MRP6 Protein, p6 Protein, CO-AG Protein, EN-RAGE Protein, S100 calcium binding protein A12 Protein, protein S100-A12 Protein, S100A12 Protein, LOC101103771 Protein

Hintergrund:

Description: The protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Name: S100A12,CAAF1,CAGC,CGRP,ENRAGE,MRP-6,MRP6,p6

Gen-ID: 6283

UniProt: P80511

Pathways: Toll-Like Receptors Cascades, S100 Proteine