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ADGRE5 (AA 21-552) protein (His tag)

Spezies: Human Wirt: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7538123
  • Target
    ADGRE5
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 21-552
    Spezies
    Human
    Quelle
    • 1
    Mammalian Cells
    Aufreinigungstag / Konjugat
    His tag
    Verwendungszweck
    Recombinant human ADGRE5 Protein with C-terminal 6xHis tag
    Spezifität
    ADGRE5 (Gln21-Arg552) 6xHis tag
    Produktmerkmale
    Extracellular Domain Protein
    Aufreinigung
    Purified from cell culture supernatant by affinity chromatography
    Reinheit
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    ADGRE5
    Synonyme
    TM7LN1 Protein, adhesion G protein-coupled receptor E5 Protein, ADGRE5 Protein
    Hintergrund
    This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
    Molekulargewicht
    predicted molecular mass of 58.9 kDa after removal of the signal peptide.
    UniProt
    P48960
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