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ADRB3 Protein

ADRB3 Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538128
  • Target Alle ADRB3 Proteine anzeigen
    ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 3
    • 3
    • 2
    Human
    Quelle
    • 4
    • 2
    • 2
    Mammalian Cells
    Verwendungszweck
    Human ADRB3 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product ADRB3 Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
    Andere Bezeichnung
    ADRB3 (ADRB3 Produkte)
    Synonyme
    BETA3AR Protein, Adrb-3 Protein, ADRB Protein, BAR3 Protein, B3AR Protein, GPCR Protein, im:7154935 Protein, si:ch211-215f19.1 Protein, zgc:194843 Protein, zgc:194852 Protein, adrenoceptor beta 3 Protein, adrenergic receptor, beta 3 Protein, adrenoceptor beta 3a Protein, adrenoceptor beta 3b Protein, ADRB3 Protein, Adrb3 Protein, adrb3a Protein, adrb3b Protein
    Hintergrund
    The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]
    Molekulargewicht
    The human full length ADRB3 protein has a MW of 43.5kDa
    UniProt
    P13945
    Pathways
    cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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