AXL Protein (AA 19-443) (His tag)

Produktnummer ABIN7538141

Produktdetails

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-443

Spezies: Maus

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses AXL Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant mouse AXL protein with C-terminal 10xHis tag

Spezifität: Mouse AXL (Ala19-Pro443) 10xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Andere Bezeichnung: AXL (AXL Produkte)

Synonyme: JTK11 Protein, UFO Protein, AI323647 Protein, Ark Protein, Tyro7 Protein, Ufo Protein, AXL receptor tyrosine kinase Protein, Axl receptor tyrosine kinase Protein, AXL Protein, Axl Protein

Hintergrund: Predicted to enable several functions, including phosphatidylinositol 3-kinase binding activity, phosphatidylserine binding activity, and virus receptor activity. Involved in negative regulation of apoptotic process and positive regulation of protein kinase B signaling. Acts upstream of or within several processes, including animal organ development, myeloid cell homeostasis, and negative regulation of tumor necrosis factor production. Predicted to be located in several cellular components, including actin cytoskeleton, cell surface, and host cell surface. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, respiratory system, and visual system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AXL (AXL receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Molekulargewicht: predicted molecular mass of 47.8 kDa after removal of the signal peptide. The apparent molecular mass of mAXL-His is 55-70 kDa due to glycosylation.

UniProt: Q00993

Pathways: RTK Signalweg, Cellular Response to Molecule of Bacterial Origin