AXL Protein (AA 33-449) (His tag)

Produktnummer ABIN7538142

Produktdetails

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 33-449

Spezies: Cynomolgus

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses AXL Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Cynomolgus AXL protein with C-terminal 10xHis tag

Spezifität: AXL (Glu33-Pro449) 10xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Andere Bezeichnung: AXL (AXL Produkte)

Synonyme: JTK11 Protein, UFO Protein, AI323647 Protein, Ark Protein, Tyro7 Protein, Ufo Protein, AXL receptor tyrosine kinase Protein, Axl receptor tyrosine kinase Protein, AXL Protein, Axl Protein

Hintergrund: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]

Molekulargewicht: predicted molecular mass of 46.5 kDa after removal of the signal peptide. The apparent molecular mass of cAXL-His is 55-70 kDa due to glycosylation.

UniProt: A0A2K5WXE0

Pathways: RTK Signalweg, Cellular Response to Molecule of Bacterial Origin