CALCRL Protein (AA 23-140) (Fc Tag)

Produktnummer ABIN7538151

Produktdetails

Target: CALCRL (Calcitonin Receptor-Like (CALCRL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-140

Spezies: Human

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses CALCRL Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant human CGRPR Protein with C-terminal human Fc tag

Spezifität: CGRPR (Glu23-Asn140) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CALCRL (Calcitonin Receptor-Like (CALCRL))

Andere Bezeichnung: CGRPR (CALCRL Produkte)

Synonyme: CALCRL Protein, CGRPR Protein, CRLR Protein, AV071593 Protein, CLR Protein, Crlr Protein, RATCRLR Protein, RNCLR Protein, calcitonin receptor like receptor Protein, calcitonin receptor-like Protein, calcitonin receptor like receptor L homeolog Protein, CALCRL Protein, LOC100168906 Protein, calcrl Protein, Calcrl Protein, calcrl.L Protein

Hintergrund: Enables adrenomedullin binding activity, adrenomedullin receptor activity, and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway, cellular response to sucrose stimulus, and receptor internalization. Located in endoplasmic reticulum, endosome, and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]

Molekulargewicht: predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-hFc is 35-70 kDa due to glycosylation.

UniProt: Q16602

Pathways: cAMP Metabolic Process