Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CCKBR Protein

CCKBR Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538194
  • Target Alle CCKBR Proteine anzeigen
    CCKBR (Cholecystokinin B Receptor (CCKBR))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 5
    • 1
    Human
    Quelle
    • 3
    • 2
    • 1
    Mammalian Cells
    Verwendungszweck
    Human GASR full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product CCKBR Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    CCKBR (Cholecystokinin B Receptor (CCKBR))
    Andere Bezeichnung
    GASR (CCKBR Produkte)
    Synonyme
    CCKBR Protein, LOC100232835 Protein, CCK-B Protein, CCK2R Protein, GASR Protein, Cck2r Protein, Cholrec Protein, CCKR-2 Protein, CCK-BR Protein, CCK2-R Protein, CCK-CHR Protein, cholecystokinin B receptor Protein, cholecystokinin receptor-like Protein, CCKBR Protein, LOC100232835 Protein, Cckbr Protein
    Hintergrund
    This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]
    Molekulargewicht
    The human full length GASR protein has a MW of 48.4kDa
    UniProt
    P32239
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour
Sie sind hier:
Kundenservice