Adipsin Protein (AA 26-253) (Fc Tag)

Produktnummer ABIN7538203

Produktdetails

Target: Adipsin (CFD) (Complement Factor D (CFD))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-253

Spezies: Human

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses Adipsin Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human CFD Protein with C-terminal human Fc tag

Spezifität: CFD (Ile26-Ala253) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Adipsin (CFD) (Complement Factor D (CFD))

Andere Bezeichnung: CFD (CFD Produkte)

Synonyme: ADIPSIN Protein, ADN Protein, DF Protein, PFD Protein, Adn Protein, Df Protein, EVE Protein, CFD Protein, adipsin Protein, pfd Protein, cfdl Protein, wu:fb61f12 Protein, zgc:109940 Protein, 10.5 Protein, 10.9 Protein, 14.10 Protein, 20.35 Protein, CG2328 Protein, Dmel\\CG2328 Protein, E(eve) Protein, Eve Protein, F Protein, V Protein, VI Protein, eve2 Protein, even Protein, l(2)46CFg Protein, l(2)46CFh Protein, l(2)46CFj Protein, l(2)46CFp Protein, l(2)46Ce Protein, l(2)46Cg Protein, complement factor D Protein, complement factor D (adipsin) Protein, complement factor D (adipsin) L homeolog Protein, even skipped Protein, CFD Protein, Cfd Protein, cfd.L Protein, cfd Protein, eve Protein

Hintergrund: This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]

Molekulargewicht: predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of CFD-hFc is 55-70 kDa due to glycosylation.

UniProt: P00746

Pathways: Komplementsystem