Complement Factor H Protein (CFH) (AA 19-1231) (His tag)

Produktnummer ABIN7538204

Produktdetails

Target: Complement Factor H (CFH)

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-1231

Spezies: Human

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses Complement Factor H Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant human CFH Protein with C-terminal 10xHis tag

Spezifität: CFH (Glu19-Arg1231) 10xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Complement Factor H (CFH)

Andere Bezeichnung: CFH (CFH Produkte)

Synonyme: AHUS1 Protein, AMBP1 Protein, ARMD4 Protein, ARMS1 Protein, CFHL3 Protein, FH Protein, FHL1 Protein, HF Protein, HF1 Protein, HF2 Protein, HUS Protein, Mud-1 Protein, NOM Protein, Sas-1 Protein, Sas1 Protein, Fh Protein, CFH Protein, im:7147412 Protein, si:ch211-207o17.2 Protein, fH Protein, armd4 Protein, arms1 Protein, cfh Protein, cfhl3 Protein, fhl1 Protein, hf1 Protein, hf2 Protein, hus Protein, complement factor H Protein, complement component factor h Protein, complement factor H-related protein 5 Protein, complement factor H L homeolog Protein, CFH Protein, Cfh Protein, cfh Protein, LOC100399888 Protein, LOC100733902 Protein, cfh.L Protein

Hintergrund: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Molekulargewicht: predicted molecular mass of 138.4 kDa after removal of the signal peptide. The apparent molecular mass of CFH-His is 130-250 kDa due to glycosylation.

UniProt: P08603

Pathways: Komplementsystem, Cellular Response to Molecule of Bacterial Origin