Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DRD4 Protein

DRD4 Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538217
  • Target Alle DRD4 Proteine anzeigen
    DRD4 (Dopamine Receptor D4 (DRD4))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 2
    • 2
    • 1
    Human
    Quelle
    • 2
    • 1
    Mammalian Cells
    Verwendungszweck
    Human DRD4 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product DRD4 Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    DRD4 (Dopamine Receptor D4 (DRD4))
    Andere Bezeichnung
    DRD4 (DRD4 Produkte)
    Synonyme
    Drd4b Protein, si:ch211-69h5.1 Protein, zgc:123021 Protein, D4DR Protein, AW125663 Protein, D4R Protein, Drd-4 Protein, D4RA Protein, DRD4 Protein, Drd4c Protein, dopamine receptor D4 related sequence Protein, dopamine receptor D4 Protein, dopamine receptor D4b Protein, drd4-rs Protein, DRD4 Protein, Drd4 Protein, SRU_2808 Protein, MSMEG_3522 Protein, drd4b Protein
    Hintergrund
    This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
    Molekulargewicht
    The human full length DRD4 protein has a MW of 43.9kDa
    UniProt
    P21917
    Pathways
    cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
Sie sind hier:
Kundenservice