ENPP2 Protein (AA 49-863) (His tag)

Produktnummer ABIN7538220

Produktdetails

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 49-863

Spezies: Human

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses ENPP2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ENPP2 Protein with N-terminal 6xHis tag

Spezifität: 6xHis tag ENPP2 (Asp49-Ile863)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Andere Bezeichnung: ENPP2 (ENPP2 Produkte)

Synonyme: ATX Protein, ATX-X Protein, AUTOTAXIN Protein, LysoPLD Protein, NPP2 Protein, PD-IALPHA Protein, PDNP2 Protein, Npps2 Protein, PD-Ialpha Protein, Pdnp2 Protein, MGC132047 Protein, atx Protein, zgc:63550 Protein, autotaxin Protein, enpp2 Protein, enpp2a Protein, enpp2b Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog Protein, ENPP2 Protein, Enpp2 Protein, enpp2 Protein, enpp2.L Protein, enpp2.S Protein

Hintergrund: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]

Molekulargewicht: predicted molecular mass of 94.5 kDa after removal of the signal peptide. The apparent molecular mass of His-ENPP2 is 100-130 kDa due to glycosylation.

UniProt: Q13822