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FZD3 Protein

FZD3 Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538245
  • Target Alle FZD3 Proteine anzeigen
    FZD3 (Frizzled Family Receptor 3 (FZD3))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    Human
    Quelle
    • 1
    Mammalian Cells
    Verwendungszweck
    Human FZD3 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product FZD3 Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    FZD3 (Frizzled Family Receptor 3 (FZD3))
    Andere Bezeichnung
    FZD3 (FZD3 Produkte)
    Synonyme
    Fz-3 Protein, FZ-3 Protein, fz3 Protein, Xfz3 Protein, frz3 Protein, hfz3 Protein, frz-3 Protein, frizzled3 Protein, frizzled-3 Protein, FZD3 Protein, AU020229 Protein, D930050A07Rik Protein, Fz3 Protein, fz9 Protein, fzd3 Protein, zg09 Protein, fzd3l Protein, frizzled class receptor 3 Protein, frizzled class receptor 3 L homeolog Protein, frizzled class receptor 3a Protein, frizzled class receptor 3b Protein, FZD3 Protein, fzd3 Protein, fzd3.L Protein, Fzd3 Protein, fzd3a Protein, fzd3b Protein
    Hintergrund
    This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]
    Molekulargewicht
    The human full length FZD3 protein has a MW of 76.3kDa
    UniProt
    Q9NPG1
    Pathways
    WNT Signalweg, Tube Formation
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