GPR107 Protein

Produktnummer ABIN7538252

Produktdetails

Target: GPR107 (G Protein-Coupled Receptor 107 (GPR107))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: Mammalian Cells

Verwendungszweck: Human GP107 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: GPR107 (G Protein-Coupled Receptor 107 (GPR107))

Andere Bezeichnung: GP107 (GPR107 Produkte)

Synonyme: wu:fi85e04 Protein, zgc:153685 Protein, MGC166006 Protein, GCDRP Protein, LUSTR1 Protein, RP11-88G17 Protein, bA138E2.2 Protein, 9930033D15Rik Protein, AI790205 Protein, C530034M11 Protein, mKIAA1624 Protein, G protein-coupled receptor 107 Protein, G protein-coupled receptor 107 S homeolog Protein, Gpr107 Protein, GPR107 Protein, gpr107.S Protein, gpr107 Protein

Hintergrund: Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (PubMed:22933024). Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).[UniProtKB/Swiss-Prot Function]

Molekulargewicht: The human full length GP107 protein has a MW of 67kDa

UniProt: Q5VW38