GPR45 Protein

Produktnummer ABIN7538277

Produktdetails

Target: GPR45 (G Protein-Coupled Receptor 45 (GPR45))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: Mammalian Cells

Verwendungszweck: Human GPR45 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: GPR45 (G Protein-Coupled Receptor 45 (GPR45))

Andere Bezeichnung: GPR45 (GPR45 Produkte)

Synonyme: GPR45 Protein, MGC97852 Protein, PSP24 Protein, PSP24(ALPHA) Protein, PSP24A Protein, 9230112G11Rik Protein, AW046772 Protein, LPA Protein, lpar-a Protein, xpsp24 Protein, G protein-coupled receptor 45 Protein, G protein-coupled receptor 45 L homeolog Protein, GPR45 Protein, gpr45 Protein, Gpr45 Protein, gpr45.L Protein

Hintergrund: This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. [provided by RefSeq, Jul 2008]

Molekulargewicht: The human full length GPR45 protein has a MW of 42kDa

UniProt: Q9Y5Y3