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GPR68 Protein

GPR68 Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538286
  • Target Alle GPR68 Produkte
    GPR68 (G Protein-Coupled Receptor 68 (GPR68))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 1
    • 1
    Human
    Quelle
    • 2
    Mammalian Cells
    Verwendungszweck
    Human OGR1 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    GPR68 (G Protein-Coupled Receptor 68 (GPR68))
    Andere Bezeichnung
    OGR1 (GPR68 Produkte)
    Synonyme
    GPR68 Protein, GPR12A Protein, OGR1 Protein, BB131428 Protein, Ogr1 Protein, G protein-coupled receptor 68 Protein, GPR68 Protein, LOC100348269 Protein, Gpr68 Protein
    Hintergrund
    The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
    Molekulargewicht
    The human full length OGR1 protein has a MW of 41.1kDa
    UniProt
    Q15743
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