GIPR Protein (AA 19-134) (Fc Tag)

Produktnummer ABIN7538299

Produktdetails

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-134

Spezies: Maus

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses GIPR Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant mouse GIPR protein with C-terminal human Fc tag

Spezifität: Mouse GIPR (Glu19-Gln134) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Andere Bezeichnung: GIPR (GIPR Produkte)

Synonyme: GIPR Protein, PGQTL2 Protein, GIP-R Protein, Gm1081 Protein, Gm160 Protein, Gippr Protein, RATGIPPR Protein, gastric inhibitory polypeptide receptor Protein, glucagon receptor Protein, GIPR Protein, LOC100303705 Protein, Gipr Protein

Hintergrund: Predicted to enable G protein-coupled peptide receptor activity, gastric inhibitory peptide receptor activity, and glucagon family peptide binding activity. Acts upstream of or within endocrine pancreas development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in foregut-midgut junction, pancreas, and pancreas primordium. Human ortholog(s) of this gene implicated in cardiovascular system disease, diabetes mellitus, obesity, and type 2 diabetes mellitus. Orthologous to human GIPR (gastric inhibitory polypeptide receptor). [provided by Alliance of Genome Resources, Apr 2022]

Molekulargewicht: predicted molecular mass of 39.5 kDa after removal of the signal peptide. The apparent molecular mass of mGIPR-hFc is 35-55 kDa due to glycosylation.

UniProt: Q0P543

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling