IGF1R Protein (AA 31-936) (His tag)

Produktnummer ABIN7538331

Produktdetails

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Protein-Typ: Recombinant

Proteineigenschaft: AA 31-936

Spezies: Maus

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses IGF1R Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant mouse IGF-1R protein with C-terminal 6xHis tag

Spezifität: Mouse IGF-1R (Glu31-His936) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Andere Bezeichnung: IGF-1R (IGF1R Produkte)

Synonyme: CMT2N Protein, CD221 Protein, IGFIR Protein, IGFR Protein, JTK13 Protein, IGFIRC Protein, IGFR1 Protein, IGF-1R Protein, IGF1R Protein, DKFZp469I0618 Protein, igf-1r Protein, xIGF-1R Protein, xIGFR Protein, xigf1r Protein, A330103N21Rik Protein, D930020L01 Protein, hyft Protein, igf-ir Protein, IGF-IR Protein, IGF-IRb Protein, wu:fb03h06 Protein, IGF-IRa Protein, sb:eu1090 Protein, wu:fi20b10 Protein, alanyl-tRNA synthetase Protein, insulin like growth factor 1 receptor Protein, insulin-like growth factor 1 receptor Protein, insulin-like growth factor 1 Protein, insulin-like growth factor I receptor Protein, insulin like growth factor 1 receptor S homeolog Protein, insulin-like growth factor 1b receptor Protein, insulin-like growth factor 1a receptor Protein, AARS Protein, IGF1R Protein, Igf1r Protein, igf1r Protein, Igf1 Protein, LOC780503 Protein, LOC100136427 Protein, igf1r.S Protein, igf1rb Protein, igf1ra Protein

Hintergrund: Enables insulin-like growth factor binding activity. Involved in several processes, including adrenal gland development, positive regulation of cold-induced thermogenesis, and positive regulation of meiotic cell cycle. Acts upstream of or within several processes, including gland development, peptidyl-tyrosine autophosphorylation, and regulation of intracellular signal transduction. Located in T-tubule. Is integral component of membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, limb, and lung. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple), kidney cancer (multiple), liver disease (multiple), nervous system cancer (multiple), and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Molekulargewicht: predicted molecular mass of 104.5 kDa after removal of the signal peptide.

UniProt: Q60751

Pathways: RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie