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EDG4 Protein

LPAR2 Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538365
  • Target Alle EDG4 (LPAR2) Proteine anzeigen
    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 2
    • 1
    Human
    Quelle
    • 2
    • 1
    Mammalian Cells
    Verwendungszweck
    Human LPAR2 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product LPAR2 Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
    Andere Bezeichnung
    LPAR2 (LPAR2 Produkte)
    Synonyme
    EDG-4 Protein, EDG4 Protein, LPA-2 Protein, LPA2 Protein, lpa2 Protein, Gpbar1 Protein, Edg4 Protein, IPA2 Protein, Pbx4 Protein, RGD1561336 Protein, zgc:101053 Protein, lysophosphatidic acid receptor 2 Protein, lysophosphatidic acid receptor 2 S homeolog Protein, G protein-coupled bile acid receptor 1 Protein, growth hormone releasing hormone receptor Protein, lysophosphatidic acid receptor 2a Protein, LPAR2 Protein, lpar2.S Protein, GPBAR1 Protein, Lpar2 Protein, GHRHR Protein, lpar2a Protein
    Hintergrund
    This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2 mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
    Molekulargewicht
    The human full length LPAR2 protein has a MW of 38.7kDa
    UniProt
    Q9HBW0
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