MCHR2 Protein

Produktnummer ABIN7538381

Produktdetails

Target: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: Mammalian Cells

Verwendungszweck: Human MCHR2 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Andere Bezeichnung: MCHR2 (MCHR2 Produkte)

Synonyme: GPR145 Protein, GPRv17 Protein, MCH-2R Protein, MCH-R2 Protein, MCH2 Protein, MCH2R Protein, MCHR-2 Protein, SLT Protein, melanin concentrating hormone receptor 2 Protein, MCHR2 Protein

Hintergrund: Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.[UniProtKB/Swiss-Prot Function]

Molekulargewicht: The human full length MCHR2 protein has a MW of 38.8kDa

UniProt: Q969V1