NPFFR1 Protein

Produktnummer ABIN7538405

Produktdetails

Target: NPFFR1 (Neuropeptide FF Receptor 1 (NPFFR1))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: Mammalian Cells

Verwendungszweck: Human NPFF1 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: NPFFR1 (Neuropeptide FF Receptor 1 (NPFFR1))

Andere Bezeichnung: NPFF1 (NPFFR1 Produkte)

Synonyme: GPR147 Protein, NPFF1 Protein, NPFF1R1 Protein, OT7T022 Protein, Gm236 Protein, Gpr147 Protein, RFRPR Protein, MGC83178 Protein, NPFFR1 Protein, LOC100230250 Protein, neuropeptide FF receptor 1 Protein, neuropeptide FF receptor 1 L homeolog Protein, inorganic pyrophosphatase-like Protein, NPFFR1 Protein, Npffr1 Protein, npffr1.L Protein, LOC100230250 Protein

Hintergrund: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]

Molekulargewicht: The human full length NPFF1 protein has a MW of 47.8kDa

UniProt: Q9GZQ6

Pathways: cAMP Metabolic Process