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NPY5R Protein

NPY5R Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538410
  • Target Alle NPY5R Proteine anzeigen
    NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 5
    • 3
    • 2
    Human
    Quelle
    • 6
    • 2
    • 2
    Mammalian Cells
    Verwendungszweck
    Human NPY5R full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product NPY5R Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))
    Andere Bezeichnung
    NPY5R (NPY5R Produkte)
    Synonyme
    NPY5-R Protein, NPYR5 Protein, NPYY5-R Protein, Y5R Protein, NPY5 Protein, MGC146705 Protein, NPY5R Protein, neuropeptide Y receptor Y5 Protein, neuropeptide Y receptor type 5 Protein, NPY5R Protein, Npy5r Protein, npy5r Protein, LOC786150 Protein
    Hintergrund
    The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]
    Molekulargewicht
    The human full length NPY5R protein has a MW of 50.7kDa
    UniProt
    Q15761
    Pathways
    Feeding Behaviour
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