OPN1SW Protein

Produktnummer ABIN7538458

Produktdetails

Target: OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: Mammalian Cells

Verwendungszweck: Human OPSB full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

Andere Bezeichnung: OPSB (OPN1SW Produkte)

Synonyme: SWS2 Protein, bluops Protein, zfblue Protein, SI:zK13A21.5 (blue-sensitive opsin) Protein, Blop Protein, GB13493 Protein, SWS1 Protein, bcp Protein, bop Protein, cbt Protein, CHK-2 Protein, BCP Protein, BOP Protein, CBT Protein, AW551857 Protein, Bcp Protein, opsin 1 (cone pigments), short-wave-sensitive 2 Protein, opsin 1, short wave sensitive Protein, blue-sensitive opsin Protein, KFH-B protein Protein, opsin 1 (cone pigments), short-wave-sensitive Protein, blue sensitive cone opsin Protein, opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) Protein, opn1sw2 Protein, OPN1SW Protein, Blop Protein, kfh-b Protein, opn1sw Protein, Opn1sw Protein, OPN2SW Protein

Hintergrund: This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. [provided by RefSeq, Jul 2008]

Molekulargewicht: The human full length OPSB protein has a MW of 38.7kDa

UniProt: P03999