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PTH2R Protein

PTH2R Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538469
  • Target Alle PTH2R Proteine anzeigen
    PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 3
    • 1
    Human
    Quelle
    • 3
    • 1
    Mammalian Cells
    Verwendungszweck
    Human PTH2R full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product PTH2R Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))
    Andere Bezeichnung
    PTH2R (PTH2R Produkte)
    Synonyme
    PTHR2 Protein, pthr2 Protein, zgc:123155 Protein, Pthr2 Protein, parathyroid hormone 2 receptor Protein, si:dkeyp-4h4.1 Protein, PTH2R Protein, pth2r Protein, Pth2r Protein, si:dkeyp-4h4.1 Protein
    Hintergrund
    The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
    Molekulargewicht
    The human full length PTH2R protein has a MW of 62.2kDa
    UniProt
    P49190
    Pathways
    cAMP Metabolic Process
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