PLA2R1 Protein (AA 21-521, AA 1097-1246) (His tag)

Produktnummer ABIN7538473

Produktdetails

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1097-1246, AA 21-521

Spezies: Human

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses PLA2R1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PLA2R1(21-521 1097-1246) Protein with C-terminal 10xHis tag

Spezifität: PLA2R1 (Glu21-Arg521 Glu1097-Leu1246) 10xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Andere Bezeichnung: PLA2R1 (PLA2R1 Produkte)

Synonyme: Pla2-r Protein, Pla2g1br Protein, Pla2r Protein, CLEC13C Protein, PLA2-R Protein, PLA2G1R Protein, PLA2IR Protein, PLA2R Protein, phospholipase A2 receptor 1 Protein, PLA2R1 Protein, Pla2r1 Protein

Hintergrund: This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

Molekulargewicht: predicted molecular mass of 76.0 kDa after removal of the signal peptide. The apparent molecular mass of PLA2R1(21-521 1097-1246)-10xHis is 70-130 kDa due to glycosylation.

UniProt: Q13018

Pathways: Positive Regulation of Response to DNA Damage Stimulus