SSR3 Protein

Produktnummer ABIN7538526

Produktdetails

Target: SSR3 (SSRg) (Signal Sequence Receptor gamma (SSRg))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: Mammalian Cells

Verwendungszweck: Human SSR3 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: SSR3 (SSRg) (Signal Sequence Receptor gamma (SSRg))

Andere Bezeichnung: SSR3 (SSRg Produkte)

Synonyme: TRAPG Protein, 0610038P07Rik Protein, AL022999 Protein, AU022074 Protein, AW553833 Protein, XTRAP-g Protein, XTRAP-gamma Protein, ssr3 Protein, ssr3-a Protein, ssr3-b Protein, ssr3a Protein, trapg Protein, fb01d07 Protein, wu:fb01d07 Protein, zgc:56300 Protein, signal sequence receptor subunit 3 Protein, signal sequence receptor, gamma Protein, signal sequence receptor, gamma (translocon-associated protein gamma) L homeolog Protein, SSR3 Protein, Ssr3 Protein, ssr3.L Protein, ssr3 Protein

Hintergrund: This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Molekulargewicht: The human full length SSR3 protein has a MW of 45.8kDa

UniProt: P32745