TIGIT Protein (AA 27-209) (Fc Tag)

Produktnummer ABIN7538539

Produktdetails

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-209

Spezies: Cynomolgus

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses TIGIT Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Cynomolgus TIGIT protein with C-terminal human Fc tag

Spezifität: TIGIT (Lys27-Pro209) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Andere Bezeichnung: TIGIT (TIGIT Produkte)

Synonyme: VSIG9 Protein, VSTM3 Protein, WUCAM Protein, ENSMUSG00000071552 Protein, Vstm3 Protein, RGD1563191 Protein, T-cell immunoreceptor with Ig and ITIM domains Protein, T cell immunoreceptor with Ig and ITIM domains Protein, TIGIT Protein, Tigit Protein

Hintergrund: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]

Molekulargewicht: predicted molecular mass of 46.6 kDa after removal of the signal peptide. The apparent molecular mass of cTIGIT-hFc is 35-55 kDa due to glycosylation.

UniProt: A0A7N9I9V4

Pathways: Cancer Immune Checkpoints