CNTNAP2 Protein (MYC tag)

Produktnummer ABIN7538792

Produktdetails

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Protein-Typ: cVLP

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CNTNAP2 Protein ist gelabelt mit MYC tag.

Applikation: Western Blotting (WB), ELISA, Nanoparticle Tracking Analysis (NTA)

Verwendungszweck: Chimeric VLP of SARS-CoV-2 (M+E+N) CASPR2

Produktmerkmale: Chimeric SARS-CoV-2 virus-like particles (cVLP) were produced in HEK cells by co-expression of the membrane-, envelope- and nucleoprotein with a membrane bound target protein. The VLPs do not contain the viral genome, cannot replicate and are not infectious.

Aufreinigung: Polyethylene glycol precipitation

Biological Activity Comment: active

Anwendungsinformationen

Applikationshinweise: Applications: Immunogenic antigen, antigen for ELISA and Western blot.
Western blot: 1-10 μg, ELISA: 1-5 μg/mL

Kommentare:

Virus-like Particles are multiprotein complexes that resemble a native virus, but lack the genetic information. Therefore, VLPs are safe to handle in numerous fields of applications. For example, VLPs can be applied as antigen in serological assays (e.g. ELISA), or serve as reference material to standardize the performance of different diagnostic tests (e.g. rapid antigen tests or ELISA). Due to the self-adjuvanting properties of VLPs is the most common application of VLPs the use as antigen for immunizations for vaccine development or antibody discovery campaigns.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS

Lagerung: -80 °C

Informationen zur Lagerung: - 80°C

Antigendetails

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Andere Bezeichnung: CNTNAP2 / CASPR2 (CNTNAP2 Produkte)

Synonyme: AUTS15 Protein, CASPR2 Protein, CDFE Protein, NRXN4 Protein, PTHSL1 Protein, 5430425M22Rik Protein, Caspr2 Protein, mKIAA0868 Protein, CASPR Protein, MGC145769 Protein, MGC147944 Protein, MGC147981 Protein, contactin associated protein like 2 Protein, contactin associated protein-like 2 Protein, contactin associated protein like 2b Protein, CNTNAP2 Protein, Cntnap2 Protein, cntnap2b Protein, cntnap2 Protein

Hintergrund: CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C omain,discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a coronavirus (genus: Betacoronavirus, subgenus: Sarbecovirus) that was identified as the cause of COVID-19 disease in early 2020.