SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein Protein

Produktnummer ABIN7538794

Produktdetails

Target: SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein

Protein-Typ: cVLP

Spezies: SARS Coronavirus-2 (SARS-CoV-2)

Quelle: HEK-293 Cells

Applikation: ELISA, Nanoparticle Tracking Analysis (NTA), Western Blotting (WB)

Verwendungszweck: Chimeric VLP of SARS-CoV-2 (M+E+N) can be used as a control

Produktmerkmale: Chimeric SARS-CoV-2 virus-like particles (cVLP) were produced in HEK cells by co-expression of the membrane-, envelope- and nucleoprotein with a membrane bound target protein. The VLPs do not contain the viral genome, cannot replicate and are not infectious.

Aufreinigung: Polyethylene glycol precipitation

Biological Activity Comment: active

Anwendungsinformationen

Applikationshinweise: Applications: Immunogenic antigen, antigen for ELISA and Western blot.
Western blot: 1-10 μg, ELISA: 1-5 μg/mL

Kommentare:

Virus-like Particles are multiprotein complexes that resemble a native virus, but lack the genetic information. Therefore, VLPs are safe to handle in numerous fields of applications. For example, VLPs can be applied as antigen in serological assays (e.g. ELISA), or serve as reference material to standardize the performance of different diagnostic tests (e.g. rapid antigen tests or ELISA). Due to the self-adjuvanting properties of VLPs is the most common application of VLPs the use as antigen for immunizations for vaccine development or antibody discovery campaigns.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS

Lagerung: -80 °C

Informationen zur Lagerung: - 80°C

Antigendetails

Target: SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein

Hintergrund: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a coronavirus (genus: Betacoronavirus, subgenus: Sarbecovirus) that was identified as the cause of COVID-19 disease in early 2020.