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IL-3 Protein

IL-3 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 98 % by SDS-PAGE and Coomassie stain Active
Produktnummer ABIN7539337
  • Target Alle IL-3 Proteine anzeigen
    IL-3 (Interleukin 3 (IL-3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 22
    • 11
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 26
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Verwendungszweck
    IL-3
    Sequenz
    ASISGRDTHR LTRTLNCSSI VKEIIGKLPE PELKTDDEGP SLRNKSFRRV NLSKFVESQG EVDPEDRYVI KSNLQKLNCC LPTSANDSAL PGVFIRDLDD FRKKLRFYMV HLNDLETVLT SRPPQPASGS VSPNRGTVEC
    Spezifität
    Chromosomal location:11 B1, 11 28.5 cM
    Kreuzreaktivität
    Bakterien, Wüstenrennmaus, Human, Affe, Maus, Ratte
    Produktmerkmale
    Length (aa):140
    Reinheit
    > 98 % by SDS-PAGE and Coomassie stain
    Endotoxin-Niveau
    < 0.1 ng/μg of protein (<1EU/μg)
    Top Product
    Discover our top product IL-3 Protein
  • Applikationshinweise
    The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is in the range of 20-100 pg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    water
    Buffer
    PBS
  • Target
    IL-3 (Interleukin 3 (IL-3))
    Andere Bezeichnung
    IL-3 (IL-3 Produkte)
    Synonyme
    BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
    Hintergrund
    Il3, BPA, PSF, HCGF, Il-3, MCGF, Csfmu,IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
    Molekulargewicht
    15.8 kDa
    Gen-ID
    16187
    NCBI Accession
    NM_010556, NP_034686
    UniProt
    P01586
    Pathways
    JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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