IL-3 Protein
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- Target Alle IL-3 Proteine anzeigen
- IL-3 (Interleukin 3 (IL-3))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Verwendungszweck
- IL-3
- Sequenz
- ASISGRDTHR LTRTLNCSSI VKEIIGKLPE PELKTDDEGP SLRNKSFRRV NLSKFVESQG EVDPEDRYVI KSNLQKLNCC LPTSANDSAL PGVFIRDLDD FRKKLRFYMV HLNDLETVLT SRPPQPASGS VSPNRGTVEC
- Spezifität
- Chromosomal location:11 B1, 11 28.5 cM
- Kreuzreaktivität
- Bakterien, Wüstenrennmaus, Human, Affe, Maus, Ratte
- Produktmerkmale
- Length (aa):140
- Reinheit
- > 98 % by SDS-PAGE and Coomassie stain
- Endotoxin-Niveau
- < 0.1 ng/μg of protein (<1EU/μg)
- Top Product
- Discover our top product IL-3 Protein
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- Applikationshinweise
- The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is in the range of 20-100 pg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- water
- Buffer
- PBS
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- Target
- IL-3 (Interleukin 3 (IL-3))
- Andere Bezeichnung
- IL-3 (IL-3 Produkte)
- Hintergrund
- Il3, BPA, PSF, HCGF, Il-3, MCGF, Csfmu,IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
- Molekulargewicht
- 15.8 kDa
- Gen-ID
- 16187
- NCBI Accession
- NM_010556, NP_034686
- UniProt
- P01586
- Pathways
- JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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