Caspase 1 Protein (CASP1)
-
- Target Alle Caspase 1 (CASP1) Proteine anzeigen
- Caspase 1 (CASP1)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
-
Spezies
- Human
-
Quelle
- Bacteria
- Produktmerkmale
- ~8000 units/mg. One unit cleaves 1 nmol of the caspase substrate YVAD-pNA per hour at 37°C in a reaction solution containing 50 mM HEPES, pH 7.2, 50 mM NaCl, 0.1% CHAPS, 10mM EDTA, 5% glycerol and 10 mM DTT.
- Top Product
- Discover our top product CASP1 Protein
-
Caspase 1 (CASP1) (AA 120-269) protein (His tag)
CASP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Caspase 1 (CASP1) (AA 120-404) protein (His tag)CASP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Caspase 1 (CASP1) (AA 1-311) protein (GST tag)CASP1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 1 (CASP1) (AA 1-100) protein (GST tag)CASP1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 1 (CASP1) (AA 120-269), (partial) protein (GST tag)CASP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute with PBS to 1 unit/µl.
- Lagerung
- -80 °C
-
- Target
- Caspase 1 (CASP1)
- Andere Bezeichnung
- Caspase-1 (CASP1 Produkte)
- Hintergrund
- Caspase-1 (also known as ICE, Interleulin-1- Converting Enzyme) is the prototypical member of the caspase family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa pro-enzyme. The pro-enzyme is matured by proteolysis to yield large (20 kDa) and small (10 kDa) subunits. The active enzyme is a heterotetramer consisting of two large and two small subunits. To date the mechanism of regulation of caspase-1 activation is complex and poorly understood. In THP-1 cells, a large proportion of the caspase-1 is present in the inactive pro-enzyme form.
- Molekulargewicht
- 45 kDa
- Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
-
