Purified native Human Cathepsin H protein Bioactivity: >1 units/mg - One unit of activity is defined as the amount of enzyme which hydrolyzes one m of L-arginine-beta-naphtylamide per minute at 40o C in 75 mM potassium phosphate bu er, pH 6.8 with 1 mM EDTA and 3 mM cysteine. Protein Source: Human liver
CTSH
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
Frozen in 20 mM CH0 OONa, pH 4.5, with 1 mM EDTA and 100 M NaCl.
Vorsichtsmaßnahmen
Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
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Hintergrund
Cathepsin H is a protein that in humans is encoded by the CTSH gene. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. Description: Human liver.