Complement Factor B Protein (CFB)

Produktnummer ABIN934807

Produktdetails

Target: Complement Factor B (CFB)

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Human

Quelle: Human

Produktmerkmale: Purified native Human Complement Factor B
Bioactivity: 4, 700 U/mg - 100 % of factor B activity in NHS on a mg/mg basis
Protein Source: Human serum/plasma

Reinheit: > 98 % pure

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.2, no preservatives added,

Konservierungsmittel: Without preservative

Vorsichtsmaßnahmen: Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Aliquot and store at -70 °C or lower.

Antigendetails

Target: Complement Factor B (CFB)

Andere Bezeichnung: Complement Factor B (CFB Produkte)

Hintergrund: Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease.
Description: Human serum/plasma.
Alternative Names: Recombinant CFB

Molekulargewicht: 93 kDa

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process